The Tampa Bay Buccaneers (6-6) hit the road to take on the San Francisco 49ers (8-4) in Week 14. Kickoff at Levy Stadium is Sunday at 4:25 p.m. ET (Fox). Below, we analyze the TPCO Sportsbook lines around Buccaneers vs. 49ers odds and our expert NFL picks and predictions. Buccaneers vs 49ers NFL.
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Buccaneers vs 49ers NFL
The Buccaneers rallied from a 2-score, 4th-quarter comeback last week for a 17-16 home win over the New Orleans Saints as 3.5-point favorites on Monday night. They have won 3 of their last 4 matches.
The 49ers, despite losing QB Jimmy Garoppolo for the rest of the season to a broken leg, won their 5th straight game last Sunday with a 33-17 victory over the Miami Dolphins.
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Buccaneers at 49ers key injuries
Buccaneers
S Mike Edwards (hamstring) doubtful
RB Leonard Fournette (foot) questionable
DL Akiem Hicks (foot) questionable
CB Sean Murphy-Bunting (quad) questionable
OL Tristan Wirfs (ankle, knee) doubtful
S Antoine Winfield (ankle) doubtful
49ers
DL Nick Bosa (hamstring) questionable
QB Jimmy Garoppolo (foot) out
DB Tarvarious Moore (knee) out
DL Hassan Ridgeway (pectoral) out
Prediction Buccaneers vs 49ers NFL
Buccaneers 20, 49ers 13
Moneyline
The 49ers have the league’s No. 1 defense in yards and points allowed. Opponents are scoring just 15.8 points per game and 283.9 yards per game. However, Tampa’s defense is no slouch, allowing just 18.3 points and 313.8 yards per game.
The Bucs are 27th in scoring at just 18.1 points per game, while the 49ers are 13th at 23.5 PPG.
Tampa 49ers have time to get ready for QB Brock Purdy. The Bucs will focus on slowing down the run game and Purdy will make plays. The 49ers are 9-29 when someone other than Garoppolo starts at QB.
It’s hard to believe that Purdy QB can surpass Tom Brady, yet the 49ers are favored. This is a great underdog bet.